Stem Cells
Stem Cells
Stem cells are the basic building blocks of all
the organs in our body. These are the undifferentiated cells which
differentiate into different specialized cell types. When an embryo comes into
origin in the womb, then it is considered that it contains a large number of
stem cells. These cells convert into various organs and form a fetus. Stem
cells have a magnificent property to change itself into any type of cell. They
can also divide themselves through mitosis to produce more stem cells. These
are found in mammals only.
They are basically of two types, embryonic stem
cells and adult stem cells. Embryonic stem cells are the inner cell mass of the
blastocysts and adult stem cells are found in various tissues of brain, bone
marrow, blood, skeletal muscles, skin and liver. In adults they remain in in
active and non-dividing state until the body is attacked by some disease or
injury.
Categories on the base of potency
Stem cells are categorized according to their
ability to divide into different types of cells. Embryonic stem cell is the
most potential as they can convert into almost all types of body cells. Potency
of adult stem cell is lesser as compared to embryonic and its potency decreases
with age.
Totipotent- They are the most potent and can convert
into all possible types of the cells. They are formed due to division of
zygote.
Pluripotent- They have a potential little lesser
than that of Totipotent one. They are found in the embryo. They are created by
embryonic cell division at the beginning of the embryo formation.
Multipotent- they can convert into cells of
closely related family. They are a type of adult stem cells.
Oligopotent- they have a low potency and can
convert into very few cells. They are also adult stem cells.
Unipotent- they cannot convert into any other type
of cell but can divide itself to produce its own type.
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